Short communication on the protective effect of probiotics on type diabetes and obesity diseases

Mariem M. Habibat

Hamdalat Biosciences, Tunis, Tunisia

Abstract

Both diabetes and obesity are life-threatening diseases that put immunity to the test. In this paper, the possibility of using probiotic organisms to control type 1 diabetes (T1D) and obesity is discussed holistically, citing relevant literature that has contributed to this notion. More studies are required using a validation lens to underscore the safety and efficacy of probiotics as agents of change or healing.

Keywords

obesity; type 1 diabetes; probiotics.

References

1. Ribeiro, F. C., Rossoni, R. D., de Barros, P. P., Santos, J. D., Fugisaki, L. R. O., Leão, M. P. V., & Junqueira, J. C. (2020). Action mechanisms of probiotics on Candida spp. and candidiasis prevention: an update. Journal of applied microbiology, 129(2), 175-185.
2. Grumet, L., Tromp, Y., & Stiegelbauer, V. (2020). The development of high-quality multispecies probiotic formulations: from bench to market. Nutrients, 12(8), 2453.
3. Wan, L. Y. M., Chen, Z. J., Shah, N. P., & El-Nezami, H. (2016). Modulation of intestinal epithelial defense responses by probiotic bacteria. Critical reviews in food science and nutrition, 56(16), 2628-2641.
4. Ashaolu, T. J. (2020). Immune boosting functional foods and their mechanisms: A critical evaluation of probiotics and prebiotics. Biomedicine & Pharmacotherapy, 130, 110625.
5. Sales-Campos, H., Soares, S. C., & Oliveira, C. J. F. (2019). An introduction of the role of probiotics in human infections and autoimmune diseases. Critical reviews in microbiology, 45(4), 413-432.
6. Strollo, R., Vinci, C., Napoli, N., Pozzilli, P., Ludvigsson, J., & Nissim, A. (2017). Antibodies to post-translationally modified insulin as a novel biomarker for prediction of type 1 diabetes in children. Diabetologia, 60(8), 1467-1474.
7. Uusitalo, U., Liu, X., Yang, J., Aronsson, C. A., Hummel, S., Butterworth, M., … & TEDDY Study Group. (2016). Association of early exposure of probiotics and islet autoimmunity in the TEDDY study. JAMA pediatrics, 170(1), 20-28.
8. Kim, T. K., Lee, J. C., Im, S. H., & Lee, M. S. (2020). Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics. Frontiers in Immunology, 11, 1832.
9. Shu, C. J., Benoist, C., & Mathis, D. (2012, December). The immune system’s involvement in obesity-driven type 2 diabetes. In Seminars in immunology(Vol. 24, No. 6, pp. 436-442). Academic Press.
10. Ley, R. E., Turnbaugh, P. J., Klein, S., & Gordon, J. I. (2006). Human gut microbes associated with obesity. nature, 444(7122), 1022-1023.
11. Kasai, C., Sugimoto, K., Moritani, I., Tanaka, J., Oya, Y., Inoue, H., … & Takase, K. (2015). Comparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing. BMC gastroenterology, 15(1), 1-10.
12. Lin, S. W., Freedman, N. D., Shi, J., Gail, M. H., Vogtmann, E., Yu, G., … & Abnet, C. C. (2015). Beta‐diversity metrics of the upper digestive tract microbiome are associated with body mass index. Obesity, 23(4), 862-869.
13. Li, B., Li, L., Li, M., Lam, S. M., Wang, G., Wu, Y., … & Speakman, J. R. (2019). Microbiota depletion impairs thermogenesis of brown adipose tissue and browning of white adipose tissue. Cell Reports, 26(10), 2720-2737.
14. Virtue, A. T., McCright, S. J., Wright, J. M., Jimenez, M. T., Mowel, W. K., Kotzin, J. J., … & Henao-Mejia, J. (2019). The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs. Science translational medicine, 11(496).
15. Fitzgibbon, G., & Mills, K. H. (2020). The microbiota and immune‐mediated diseases: Opportunities for therapeutic intervention. European journal of immunology, 50(3), 326-337.
16. Walsh, C. J., Healy, S., O’Toole, P. W., Murphy, E. F., & Cotter, P. D. (2020). The probiotic L. casei LC-XCAL™ improves metabolic health in a diet-induced obesity mouse model without altering the microbiome. Gut microbes, 12(1), 1747330.
17. Cheng, Y. C., & Liu, J. R. (2020). Effect of Lactobacillus rhamnosus GG on energy metabolism, leptin resistance, and gut microbiota in mice with diet-induced obesity. Nutrients, 12(9), 2557.
18. Gan, Y., Chen, H., Zhou, X. R., Chu, L. L., Ran, W. T., Tan, F., & Zhao, X. (2020). Regulating effect of Lactobacillus plantarum CQPC03 on lipid metabolism in high‐fat diet‐induced obesity in mice. Journal of Food Biochemistry, 44(11), e13495.
19. Yan, P. G., & Li, J. N. (2020). Advances in the understanding of the intestinal micro-environment and inflammatory bowel disease. Chinese medical journal, 133(7), 834.
20. Swierz, M. J., Storman, D., Staskiewicz, W., Gorecka, M., Jasinska, K. W., Swierz, A. M., … & Bala, M. M. (2020). Efficacy of probiotics in patients with morbid obesity undergoing bariatric surgery-systematic review and meta-analysis. Surgery for Obesity and Related Diseases.
21. Zhao, D., Gao, F., Zhu, H., Qian, Z., Mao, W., Yin, Y., & Chen, D. (2020). Selenium-enriched Bifidobacterium longum DD98 relieves metabolic alterations and liver injuries associated with obesity in high-fat diet-fed mice. Journal of Functional Foods, 72, 104051.
22. Mishra, A. K., & Ghosh, A. R. (2020). Probiotic Enterococcus faecalis AG5 mitigated high fat diet induced obesity and produced propionic acid stimulated apoptosis in 3T3-L1 pre-adipocyte. Life Sciences, 261, 118292
23. Soundharrajan, I., Kuppusamy, P., Srisesharam, S., Lee, J. C., Sivanesan, R., Kim, D., & Choi, K. C. (2020). Positive metabolic effects of selected probiotic bacteria on diet‐induced obesity in mice are associated with improvement of dysbiotic gut microbiota. The FASEB Journal, 34(9), 12289-12307.
24. Bai, L., Kumar, S., Verma, S., & Seshadri, S. (2020). Bacteriocin PJ4 from probiotic lactobacillus reduced adipokine and inflammasome in high fat diet induced obesity. 3 Biotech, 10(8), 1-10.